See how research connects peptides to biological targets, signaling pathways, and biological processes.
This tool shows, for each peptide, which biological target the available research points to, how directly that relationship is supported, and how it connects to broader signaling pathways and biological processes. It describes what research suggests about biological mechanisms -- not proven health or treatment outcomes, and not medical advice. See each peptide's full research profile for complete detail, citations, and safety information.
The complete mechanism research history, including peptides outside the current catalog. Nothing here has been removed or invalidated -- it remains fully documented for reference.
Showing 83 of 83 peptides
Evidence legend
Relationship support
Directly supported
Supported indirectly
Inferred from related evidence
Uncertain
Evidence context
Human research
Preclinical research
Human + preclinical research
Review / established literature
Related compound/program context
Evidence context uncertain
Understanding mechanism evidence
This tool describes research into biological targets, signaling pathways, and biological processes -- not proven health or treatment outcomes, and not medical advice. Relationship-support and evidence-context labels describe the type and directness of research available, not proof of safety or effectiveness. See each peptide's full research profile for complete detail, citations, and safety information.
Mechanism profiles
Dermorphin
1 mechanism relationship · Directly supported · Preclinical research
Dermorphin → Mu-opioid receptor — Directly supportedDermorphin is a potent mu-opioid agonist; naloxone blocked physiological effects in human endocrine experiments.
Evidence context
Preclinical research
Receptor pharmacology does not establish a favorable therapeutic index compared with approved opioids.
Sources
Central Citation Library reference: b08-derm-03-prolactin-releasing-activity-of-dermorphin-a-new-synth
Central Citation Library reference: b08-derm-02-pharmacological-data-on-dermorphins-a-new-class-of-pot
What is established
A target (Mu-opioid receptor) and pathway family (Neuropeptide & CNS Signaling) are documented.
What remains unclear
Specific downstream signaling steps and biological-process associations are not yet documented.
Receptor pharmacology does not establish a favorable therapeutic index compared with approved opioids.
Key terms
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Peptide Explorer shows what areas a peptide is researched in. This tool shows how the underlying biology appears to work.
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